Ga68PSMa PET in a patient with recurrent prostate cancer. At the arrowhead: a lymph node metastasis. Acquisition parameters: 3 min/bed position on the Gemini 64 ToF, 60 min after injection of 2 MBq/kg of Ga68PSMA. Images courtesy of the St. Antonius hospital, Nieuwegein, the Netherlands.
Although Gallium-68 is not a particularly challenging isotope to image, clinicians at the St. Antonius are happy with their Philips PET/CT scanner with TOF. It was very easy to set up for the new isotope, and the TOF functionality makes the high contrast of Gallium-68-labeled tracers even more striking. Lavalaye: “We have shown that Ga68PSMA is so sensitive, that it can show lymph node metastases in nodes of 5 mm and smaller, therefore camera resolution is crucial for Ga68PSMA PET imaging. For small metastases centrally in the abdomen, especially in obese patients, the time-of-flight technique is really rewarding.”